Cerebral vasospasm in a double-injection model in rabbit
نویسندگان
چکیده
منابع مشابه
Ultrasound guided double injection of blood into cisterna magna: a rabbit model for treatment of cerebral vasospasm.
BACKGROUND Double injection of blood into cisterna magna using a rabbit model results in cerebral vasospasm. An unacceptably high mortality rate tends to limit the application of model. Ultrasound guided puncture can provide real-time imaging guidance for operation. The aim of this paper is to establish a safe and effective rabbit model of cerebral vasospasm after subarachnoid hemorrhage with t...
متن کاملCORRELATION BE TWEEN ENDOTHELIAL INJURY AND CEREBRAL VASOSPASM FOLLOWING A DOUBLE SUBARACHNOID HEMORRHAGE IN THE RAT
While a wide array of pathological changes occur in cerebral arteries following subarachnoid hemorrhage (SAH), the most consistent is endothelial damage. Since the endothelium normally modulates reflexes that influence vascular tone, any damage to it may represent a significant contributor to cerebral vasospasm following SAH. This experimental study investigates the correlation between end...
متن کاملMR-angiography allows defining severity grades of cerebral vasospasm in an experimental double blood injection subarachnoid hemorrhage model in rats
OBJECTIVE Magnetic resonance (MR) imaging has been used for the detection of cerebral vasospasm (VSP) related infarction in experimental subarachnoid hemorrhage (eSAH) in rats. Conventional angiography is generally used to visualize VSP, which is an invasive technique with a possible increase in morbidity and mortality. In this study we evaluated the validity of MR-angiography (MRA) in detectin...
متن کاملClentiazem protects against chronic cerebral vasospasm in rabbit basilar artery.
BACKGROUND AND PURPOSE Experiments were carried out in rabbits to determine whether clentiazem (8-chlorodiltiazem), a cerebrovascular-selective calcium channel blocker, administered 24 hours before subarachnoid hemorrhage influenced the subsequent cerebral vasospasm. METHODS Subarachnoid hemorrhage was induced by multiple injections of blood into the prepontine cisterns of 35 male New Zealand...
متن کاملcorrelation be tween endothelial injury and cerebral vasospasm following a double subarachnoid hemorrhage in the rat
while a wide array of pathological changes occur in cerebral arteries following subarachnoid hemorrhage (sah), the most consistent is endothelial damage. since the endothelium normally modulates reflexes that influence vascular tone, any damage to it may represent a significant contributor to cerebral vasospasm following sah. this experimental study investigates the correlation between endothel...
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ژورنال
عنوان ژورنال: Surgical Neurology
سال: 1989
ISSN: 0090-3019
DOI: 10.1016/0090-3019(89)90002-5